Inflammatory cytokines in an experimental model for the multiple organ dysfunction syndrome

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Inflammatory cytokines in an experimental model for the multiple organ dysfunction syndrome.

OBJECTIVE To investigate the alterations in circulating pro-inflammatory cytokines and cytokine production by peritoneal macrophages during the development of multiple organ dysfunction syndrome. DESIGN Prospective, controlled laboratory study on zymosan-induced generalized inflammation in mice. Single intraperitoneal administration of zymosan induces, over a 12-day period, a triphasic illnes...

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ژورنال

عنوان ژورنال: Critical Care Medicine

سال: 1996

ISSN: 0090-3493

DOI: 10.1097/00003246-199607000-00022